California

Lightstone Ventures

Lightstone Ventures backs life sciences and healthtech startups from Pre-Seed to Series B, leading investments from its California base, with a $375 million latest fund.

Entry stagePre-seed, Seed, Series A, Series B
Check sizen/a
Leads roundsn/a
FocusLife sciences, Healthtech
Latest fund$375 (2021)$375 million (Lightstone Ventures III) (2021)
Investing team7 peopleNo activity since Sep

Who you would pitch at Lightstone Ventures

7 people on the investing team, 6 of them partners who can make the call. Partners are listed first.

Work here and something is wrong? Ask for a correction.

Check size not reported yet.

Bars: how many firms in the atlas report each band. Highlighted: this firm.

No recent activity since September 2026. Quiet does not mean closed.

Weekly count of activity updates. Activity is not a confirmed deal.

Notable investments

Vigil NeuroscienceALX OncologyNimbus TherapeuticsMicroVentionCala HealthVolta MedicalCoolSculpting (ZELTIQ)Carrick Therapeutics
Founders and investors at a Mode VC gathering

Send Mode VC your deck

Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

Send your deck

Alert me when Lightstone Ventures is active

One email when this firm shows new activity. Nothing else.

Firms like Lightstone Ventures

On these lists

Questions

What stage does Lightstone Ventures invest in?

Lightstone Ventures reports entry at pre-seed, seed, series a, series b.

How much does Lightstone Ventures invest?

Lightstone Ventures has not reported a check size.

Does Lightstone Ventures lead rounds?

Lightstone Ventures has not reported a lead preference.

Who are the partners at Lightstone Ventures?

Hank Plain (Founding Partner), Jean George (Managing Partner), Mike Carusi (Managing Partner), Caroline Gaynor (Partner), Christina Isacson (Partner), Hanson Gifford III (Partner).

Is Lightstone Ventures active right now?

No recent activity since September 2026.

Work at Lightstone Ventures? Claim or correct this profile.