Mode VC
New York

Signet Healthcare Partners

Signet Healthcare Partners, based in New York, backs life sciences and healthtech companies at Series B, can lead rounds, and writes checks from $10 million to over $30 million.

WebsitePortfolioPitch pageTeam page
Entry stageSeries B
Check size$10M to $30M+
Leads roundsYes
FocusLife sciences, Healthtech
Latest fund$600M+$600M+ cumulative fund commitments
Investing team5 peopleNo activity since Sep

Who you would pitch at Signet Healthcare Partners

5 people on the investing team, 3 of them partners who can make the call. Partners are listed first.

Ashley Friedman
Ashley FriedmanManaging DirectorHe focuses on growth equity in medical devices and pharmaceuticals, with prior roles at Investor Growth Capital and Lehman Brothers.
James Gale
James GaleFounding Partner & Managing DirectorHe joined Primrose Bio's Board of Directors after Signet led a financing round in the company, with participation from existing investors.
Nikhil Puri
Nikhil PuriManaging DirectorHe previously led business development for Pfizer's Global Established Pharmaceuticals and worked at Lehman Brothers and Bear Stearns.
Emad Piracha
Emad PirachaVice PresidentFocus: investment activities and portfolio oversight.
Audrey Liu
Audrey LiuAssociateFocus: investment activities.

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Writes $10M to $30M+ checks. Its smallest check is larger than 97% of firms in the atlas.

Bars: how many firms in the atlas report each band. Highlighted: this firm.

No recent activity since September 2026. Quiet does not mean closed.

Weekly count of activity updates. Activity is not a confirmed deal.

Before you pitch

Ownership target7-10%

Notable investments

TELA BioEyePoint PharmaceuticalsAlta SciencesLeading Pharma

In their words

Signet Healthcare Partnerswww.signethealthcarepartners.com
Founders and investors at a Mode VC gathering

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Firms like Signet Healthcare Partners

HealthQuest Capital$10M to $30M+
MVM Life Science Partners$10M to $30M+
Vensana Capital$10M to $30M+
OrbiMed$1M to $30M+
Telegraph Hill Partners$10M to $30M
Evidity Health Capital$3M to $10M

On these lists

Series B healthtech investors in New York22Series B life sciences investors in New York20Series B investors in United States563Series B healthtech investors128Series B investors in New York123Series B life sciences investors91Series B investors604

Questions

What stage does Signet Healthcare Partners invest in?

Signet Healthcare Partners reports entry at series b.

How much does Signet Healthcare Partners invest?

Signet Healthcare Partners reports checks of $10M to $30M+.

Does Signet Healthcare Partners lead rounds?

Yes. Signet Healthcare Partners says it can lead.

Who are the partners at Signet Healthcare Partners?

Ashley Friedman (Managing Director), James Gale (Founding Partner & Managing Director), Nikhil Puri (Managing Director).

Is Signet Healthcare Partners active right now?

No recent activity since September 2026.

Work at Signet Healthcare Partners? Claim or correct this profile.