Ann DeWitt

Ann DeWitt

General Partner atThe EngineFirm active Sep 22Massachusetts

Ann DeWitt is a General Partner at Engine Ventures, an experienced executive, investor, and advisor. She serves on multiple boards and previously held senior roles at Sanofi and Flagship Pioneering.

What Ann can write

Writes checks of$250K to $10M
Comes in atPre-seed, Seed, Series ACan lead the round
Ownership target7-10%At first check
Email the firm[email protected]The firm's own inbox for founders.

The Engine writes $250K to $10M checks, larger than 33% of firms in the atlas.

Bars: how many firms report each check band. Highlighted: The Engine.

Career

  1. 3M · R&D
  2. Flagship Pioneering
  3. Sanofi · senior roles in business development and strategic venture investment
  4. Engine Ventures · General Partner
    Now
  5. Flagship Pioneering · part of the team

Investments named in public bios

CellinoDroplet BiosciencesMatrisome BioSource BioPredicta BiosciencesBexorgTerrestrial Bio

Focus

life sciencesventure investmentbusiness development

Education

MIT, PhD in Chemical EngineeringHarvard Business School, MBA

Also at The Engine

Partners like Ann

At firms with a similar stage, sector and check size.

Alert me when The Engine is active

One email when Ann's firm raises a fund, adds a partner or shows new activity.

Founders and investors at a Mode VC gathering

Send Mode VC your deck

Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

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Questions

Who is Ann DeWitt?

Ann DeWitt is a General Partner at Engine Ventures, an experienced executive, investor, and advisor. She serves on multiple boards and previously held senior roles at Sanofi and Flagship Pioneering.

How much does Ann DeWitt invest?

Ann DeWitt invests through The Engine, which writes checks of $250K to $10M at pre-seed, seed, series a.

How do I pitch Ann DeWitt?

Email [email protected], the firm's inbox for founders, and name Ann in the subject. A warm intro from a founder The Engine backed works better.

What did Ann DeWitt do before The Engine?

R&D at 3M; Flagship Pioneering; senior roles in business development and strategic venture investment at Sanofi; part of the team at Flagship Pioneering.

Last updated 2026-10-15. Is this you? Ask for a correction.