David Smoller

David Smoller

General Partner atCultivation CapitalMissouri

David Smoller is a serial entrepreneur and life sciences executive who founded multiple biotech companies. He currently serves as an Operating Partner at Cultivation Capital and Entrepreneur in Residence at BioGenerator Ventures and Washington University.

What David can write

Writes checks of$100K to $10M
Comes in atSeed, Series A, Series BCan lead the round
Email the firm[email protected]The firm's own inbox for founders.

Cultivation Capital writes $100K to $10M checks, larger than 5% of firms in the atlas.

Bars: how many firms report each check band. Highlighted: Cultivation Capital.

Career

  1. SAGE Labs · Founder and CEO
    until 2014
  2. Horizon Discovery · Chief Business Officer and Board Member
    2014-2015
  3. Canopy Biosciences · Co-founder
    2016-2020
  4. BioGenerator Ventures · Entrepreneur in Residence
  5. Washington University’s New Ventures group · Entrepreneur in Residence
  6. Cultivation Capital · Operating Partner
    Now
  7. Sigma-Aldrich · Chief Scientific Officer
    2004-2012
  8. Cultivation Capital · General Partner
    Now

Companies founded

Canopy BiosciencesSAGE LabsProteoPlexGenome Systems

Focus

biotechnologylife sciencesgene-editinggenomics

Education

Emory University, PhD in Molecular Biology

Also at Cultivation Capital

Partners like David

At firms with a similar stage, sector and check size.

Alert me when Cultivation Capital is active

One email when David's firm raises a fund, adds a partner or shows new activity.

Founders and investors at a Mode VC gathering

Send Mode VC your deck

Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

Send your deck

Questions

Who is David Smoller?

David Smoller is a serial entrepreneur and life sciences executive who founded multiple biotech companies. He currently serves as an Operating Partner at Cultivation Capital and Entrepreneur in Residence at BioGenerator Ventures and Washington University.

How much does David Smoller invest?

David Smoller invests through Cultivation Capital, which writes checks of $100K to $10M at seed, series a, series b.

How do I pitch David Smoller?

Email [email protected], the firm's inbox for founders, and name David in the subject. A warm intro from a founder Cultivation Capital backed works better.

What did David Smoller do before Cultivation Capital?

Founder and CEO at SAGE Labs; Chief Business Officer and Board Member at Horizon Discovery; Co-founder at Canopy Biosciences; Entrepreneur in Residence at BioGenerator Ventures; Entrepreneur in Residence at Washington University’s New Ventures group; Chief Scientific Officer at Sigma-Aldrich.

Last updated 2026-10-15. Is this you? Ask for a correction.