J. Matthew Mackowski

J. Matthew Mackowski

Chairman, Managing Director atTelegraph Hill PartnersSan Francisco

Matt Mackowski has been a healthcare-focused venture capital investor since 1980, starting at Citicorp Venture Capital. He formed Mackowski & Shepler in 1991, the predecessor to Telegraph Hill Partners, where he is now Chairman and Managing Director.

What J. can write

Writes checks of$10M to $30M
Comes in atSeries A, Series BCan lead the round
Ownership target7-10%At first check
Email the firm[email protected]The firm's own inbox for founders.

Telegraph Hill Partners writes $10M to $30M checks, larger than 97% of firms in the atlas.

Bars: how many firms report each check band. Highlighted: Telegraph Hill Partners.

Career

  1. Citicorp Venture Capital · investment professional
    1980-1991
  2. Mackowski & Shepler
    1991
  3. Telegraph Hill Partners · Chairman, Managing Director
    Now
  4. Mackowski & Shepler
  5. Alpha Teknova, Inc. · Director
    2019-null

Companies founded

Mackowski & SheplerTelegraph Hill Partners

Investments named in public bios

Althea TechnologiesAmbionAsuragenEmerging Therapy SolutionsInterface AssociatesKinetikos MedicalMagstimMedPricerTeknovaTrakCelNimble Therapeutics

Focus

healthcaremedical technologieslife science technologieslife sciencesmedical device

Education

Duke University, BAThe Wharton School, MBA

Also at Telegraph Hill Partners

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At firms with a similar stage, sector and check size.

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One email when J.'s firm raises a fund, adds a partner or shows new activity.

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Questions

Who is J. Matthew Mackowski?

Matt Mackowski has been a healthcare-focused venture capital investor since 1980, starting at Citicorp Venture Capital. He formed Mackowski & Shepler in 1991, the predecessor to Telegraph Hill Partners, where he is now Chairman and Managing Director.

How much does J. Matthew Mackowski invest?

J. Matthew Mackowski invests through Telegraph Hill Partners, which writes checks of $10M to $30M at series a, series b.

How do I pitch J. Matthew Mackowski?

Email [email protected], the firm's inbox for founders, and name J. in the subject. A warm intro from a founder Telegraph Hill Partners backed works better.

What did J. Matthew Mackowski do before Telegraph Hill Partners?

investment professional at Citicorp Venture Capital; Mackowski & Shepler; Mackowski & Shepler; Director at Alpha Teknova, Inc..

Last updated 2026-10-15. Is this you? Ask for a correction.