John Flavin is a founder and CEO with experience developing corporate, academic, and civic enterprises. He has raised over $345 million in private and philanthropic capital for transformative organizations.

What John can write

Writes checks of$500K to $3M
Comes in atPre-seed, SeedCan lead the round
Email the firm[email protected]The firm's own inbox for founders.

Portal Innovations writes $500K to $3M checks, larger than 71% of firms in the atlas.

Bars: how many firms report each check band. Highlighted: Portal Innovations.

Career

  1. Pyxis Oncology · Co-Founder and Chairman
  2. ClostraBio · Executive Chairman
  3. Grove Biopharma · Board member
  4. Advanced Life Sciences
  5. MediChem
  6. MATTER
  7. Polsky Center for Entrepreneurship and Innovation at the University of Chicago
  8. Portal Innovations · Founder & CEO
    Now

Companies founded

Advanced Life SciencesChicago Innovation MentorsMATTERPolsky Center for Entrepreneurship and Innovation at the University of ChicagoPortal InnovationsPyxis Oncology

Investments named in public bios

Pyxis OncologyClostraBioGrove Biopharma

Focus

biotechentrepreneurshipinnovationlife sciencescommercialization

Also at Portal Innovations

Partners like John

At firms with a similar stage, sector and check size.

Alert me when Portal Innovations is active

One email when John's firm raises a fund, adds a partner or shows new activity.

Founders and investors at a Mode VC gathering

Send Mode VC your deck

Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

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Questions

Who is John Flavin?

John Flavin is a founder and CEO with experience developing corporate, academic, and civic enterprises. He has raised over $345 million in private and philanthropic capital for transformative organizations.

How much does John Flavin invest?

John Flavin invests through Portal Innovations, which writes checks of $500K to $3M at pre-seed, seed.

How do I pitch John Flavin?

Email [email protected], the firm's inbox for founders, and name John in the subject. A warm intro from a founder Portal Innovations backed works better.

What did John Flavin do before Portal Innovations?

Co-Founder and Chairman at Pyxis Oncology; Executive Chairman at ClostraBio; Board member at Grove Biopharma; Advanced Life Sciences; MediChem; MATTER; Polsky Center for Entrepreneurship and Innovation at the University of Chicago.

Last updated 2026-10-15. Is this you? Ask for a correction.