John Prufeta

John Prufeta

Founder, CEO & Managing Partner atMedical Excellence CapitalNew York

John Prufeta founded Medical Excellence Capital in 2020 and serves as CEO and Managing Partner. He has over 30 years of experience as an operator and consultant to academic medical centers.

What John can write

Writes checks of$3M to $30M
Comes in atPre-seed, Seed, Series A, Series BCan lead the round
Ownership target> 12%At first check
Pitch pageSubmit on their siteThe firm asks founders to apply here.

Medical Excellence Capital writes $3M to $30M checks, larger than 93% of firms in the atlas.

Bars: how many firms report each check band. Highlighted: Medical Excellence Capital.

Career

  1. Agilence Health Advisors · Managing Partner
  2. OnPoint Partners · Managing Partner
  3. Medix Resources · President and CEO
    2000-2003
  4. Medical Excellence Group · Chairman
    Now
  5. Medical Excellence Capital · Chief Executive Officer and Managing Partner
    Now
  6. Medical Excellence Capital · Founder, CEO & Managing Partner
    Now

Companies founded

Medical Excellence CapitalMedical Excellence Group

Investments named in public bios

CuraLeaf

Focus

health careacademic medical centerspreventative medicinetelemedicinelongevityhealthcare investment

Education

Harvard University Graduate School of Business, Harvard Executive Program, OPM 28St. John's University

Also at Medical Excellence Capital

Partners like John

At firms with a similar stage, sector and check size.

Alert me when Medical Excellence Capital is active

One email when John's firm raises a fund, adds a partner or shows new activity.

Founders and investors at a Mode VC gathering

Send Mode VC your deck

Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

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Questions

Who is John Prufeta?

John Prufeta founded Medical Excellence Capital in 2020 and serves as CEO and Managing Partner. He has over 30 years of experience as an operator and consultant to academic medical centers.

How much does John Prufeta invest?

John Prufeta invests through Medical Excellence Capital, which writes checks of $3M to $30M at pre-seed, seed, series a, series b.

How do I pitch John Prufeta?

A warm intro from a founder Medical Excellence Capital backed works best. A short LinkedIn note with one line on traction is the next best route.

What did John Prufeta do before Medical Excellence Capital?

Managing Partner at Agilence Health Advisors; Managing Partner at OnPoint Partners; President and CEO at Medix Resources.

Last updated 2026-10-15. Is this you? Ask for a correction.