Rob Hopfner is a venture capital professional based in San Francisco. He currently serves as a Managing Director and Managing Partner at Pivotal firms.

What Rob can write

Writes checks of$3M to $30M
Comes in atPre-seed, Seed, Series A, Series BCan lead the round
Ownership target7-10%, 10-12%At first check
Pitch pageSubmit on their siteThe firm asks founders to apply here.

Pivotal bioVenture Partners writes $3M to $30M checks, larger than 93% of firms in the atlas.

Bars: how many firms report each check band. Highlighted: Pivotal bioVenture Partners.

Career

  1. DuPont / Merck Pharmaceuticals
  2. Bay City Capital · Managing Director
  3. Pivotal Life Sciences · Managing Director
    2017-null
  4. Pivotal bioVenture Partners (US) · Managing Partner
    Now

Investments named in public bios

Aciex TherapeuticsArcutis TherapeuticsAvalyn PharmaCivitas TherapeuticsDermiraExscientiaGracellHyperion TherapeuticsInozymeKaruna TherapeuticsLB PharmaMadrigal PharmaceuticalsMerus BVNextWave PharmaceuticalsObsidian TherapeuticsOculis

Focus

Venture Capital

Education

University of Saskatchewan, RPh in PharmacyUniversity of Saskatchewan, PhD in PharmacologyUniversity of Chicago Booth School of Business, MBAHarvard Medical School

Also at Pivotal bioVenture Partners

Partners like Rob

At firms with a similar stage, sector and check size.

Alert me when Pivotal bioVenture Partners is active

One email when Rob's firm raises a fund, adds a partner or shows new activity.

Founders and investors at a Mode VC gathering

Send Mode VC your deck

Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

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Questions

Who is Rob Hopfner?

Rob Hopfner is a venture capital professional based in San Francisco. He currently serves as a Managing Director and Managing Partner at Pivotal firms.

How much does Rob Hopfner invest?

Rob Hopfner invests through Pivotal bioVenture Partners, which writes checks of $3M to $30M at pre-seed, seed, series a, series b.

How do I pitch Rob Hopfner?

A warm intro from a founder Pivotal bioVenture Partners backed works best. A short LinkedIn note with one line on traction is the next best route.

What did Rob Hopfner do before Pivotal bioVenture Partners?

DuPont / Merck Pharmaceuticals; Managing Director at Bay City Capital; Managing Director at Pivotal Life Sciences.

Last updated 2026-10-15. Is this you? Ask for a correction.