New York

Apple Tree Partners

Apple Tree Partners, based in New York, backs life sciences companies from Pre-Seed to Series B, mostly leading rounds with checks from $10 million to over $30 million.

Entry stagePre-seed, Seed, Series A, Series B
Check size$10M to $30M+
Leads roundsYes
FocusLife sciences
Latest fund$2.9B committed capital
Investing team3 peopleNo activity since Sep

Who you would pitch at Apple Tree Partners

3 people on the investing team, 2 of them partners who can make the call. Partners are listed first.

Work here and something is wrong? Ask for a correction.

Writes $10M to $30M+ checks. Its smallest check is larger than 97% of firms in the atlas.

Bars: how many firms in the atlas report each band. Highlighted: this firm.

No recent activity since September 2026. Quiet does not mean closed.

Weekly count of activity updates. Activity is not a confirmed deal.

Before you pitch

Ownership target7-10%
How to reach them[email protected]

Notable investments

Akero TherapeuticsChinook TherapeuticsStoke TherapeuticsAileron TherapeuticsHeartWare InternationalCorvidia TherapeuticsSyntimmuneVytronUSTusker MedicalSGX Pharmaceuticals

In their words

Homewww.appletreepartners.com
Founders and investors at a Mode VC gathering

Send Mode VC your deck

Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

Send your deck

Alert me when Apple Tree Partners is active

One email when this firm shows new activity. Nothing else.

Firms like Apple Tree Partners

On these lists

Questions

What stage does Apple Tree Partners invest in?

Apple Tree Partners reports entry at pre-seed, seed, series a, series b.

How much does Apple Tree Partners invest?

Apple Tree Partners reports checks of $10M to $30M+.

Does Apple Tree Partners lead rounds?

Yes. Apple Tree Partners says it can lead.

Who are the partners at Apple Tree Partners?

Seth L. Harrison (Founder and Managing Partner), Anna Batarina (Partner).

Is Apple Tree Partners active right now?

No recent activity since September 2026.

Work at Apple Tree Partners? Claim or correct this profile.