New York

Catalio Capital Management

Catalio Capital Management, based in New York, backs life sciences and healthtech startups from Pre-Seed to Series B, can lead rounds, and has a $2B fund.

Entry stagePre-seed, Seed, Series A, Series B
Check sizen/a
Leads roundsYes
FocusLife sciences, Healthtech
Latest fund$2B AUM
Investing team20 peopleNo activity since Sep

Who you would pitch at Catalio Capital Management

20 people on the investing team, 9 of them partners who can make the call. Partners are listed first.

George C. Petrocheilos
George C. PetrocheilosCo-Founder & Managing PartnerHe previously was a General Partner at Camden Partners Holdings, LLC.
R. Jacob Vogelstein, Ph.D.
R. Jacob Vogelstein, Ph.D.Co-Founder & Managing PartnerHe previously was a General Partner at Camden Partners and served on the faculty at Johns Hopkins University.
Ajay Mantha
Ajay ManthaPartnerHe previously held roles at Zimmer Partners, Bain Capital, D.E.
Ben Snedeker
Ben SnedekerPartner & Head of Public EquitiesHe previously held roles at HealthCor Management, PointState Capital, D.E.
Diamantis Xylas, M.D.
Diamantis Xylas, M.D.Partner & Head of ResearchHe previously trained in surgery and researched at Weill Cornell.
Hai Yan, Ph.D.
Hai Yan, Ph.D.PartnerHe is also a professor at A*STAR and co-founded Genetron Health.
Isaac Ro
Isaac RoPartnerHe previously held CFO roles at Sema4 and Thrive Earlier Detection, and led equity research at Goldman Sachs.
John Henry Iucker, CFA
John Henry Iucker, CFAPartner & Head of CreditFocus: structured credit for healthcare and biotech firms.
Tom Brooks
Tom BrooksPartnerHe previously held executive roles at Constellation Energy Group and worked at Goldman Sachs.
Matthew Hobson, Ph.D.
Matthew Hobson, Ph.D.PrincipalFocus: therapeutics and diagnostics investments.
Nicholas von Guionneau, M.D.
Nicholas von Guionneau, M.D.PrincipalHe focuses on breakthrough medical technologies and clinical care delivery, and holds board observer roles at several companies.
Pasquale Chiacchiari
Pasquale ChiacchiariPrincipal & Head of Data ScienceFocus: data science and AI in healthcare investments.
Sean Wang
Sean WangPrincipalHe previously held roles at Oaktree, Ares, Athyrium, and Guggenheim.
Vicky Sostilio
Vicky SostilioVice President, North AmericaShe previously led investor relations at HealthCor Management and worked at UBS.
Will Denehy
Will DenehyVice President, EuropeHe previously held roles at Odey Asset Management and Fisher Investments.
Brian Malik, Ph.D.
Brian Malik, Ph.D.Senior AnalystHe previously held roles at T.
Collin Spencer, Ph.D.
Collin Spencer, Ph.D.AssociateFocus: AI-enabled healthcare investments.
Constantine Alexos
Constantine AlexosAnalystHe previously worked in healthcare investment banking at Goldman, Sachs & Co. and holds a finance degree from Indiana University.
David Stonko, M.D.
David Stonko, M.D.Clinical Associate
Trent Murphy
Trent MurphyAnalyst

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Check size not reported yet.

Bars: how many firms in the atlas report each band. Highlighted: this firm.

No recent activity since September 2026. Quiet does not mean closed.

Weekly count of activity updates. Activity is not a confirmed deal.

Before you pitch

Ownership target7-10%
How to reach them[email protected]

Notable investments

ArriVent BioPharmaDianthus TherapeuticsNeumora TherapeuticsCompass PathwaysPaige

In their words

Catalio Capital ManagementCatalio Capital Management was created by George Petrocheilos and Dr. Jacob Vogelstein to invest in breakthrough biomedical technology companies created or referred by Cawww.cataliocapital.com
Founders and investors at a Mode VC gathering

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One email when this firm shows new activity. Nothing else.

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Questions

What stage does Catalio Capital Management invest in?

Catalio Capital Management reports entry at pre-seed, seed, series a, series b.

How much does Catalio Capital Management invest?

Catalio Capital Management has not reported a check size.

Does Catalio Capital Management lead rounds?

Yes. Catalio Capital Management says it can lead.

Who are the partners at Catalio Capital Management?

George C. Petrocheilos (Co-Founder & Managing Partner), R. Jacob Vogelstein, Ph.D. (Co-Founder & Managing Partner), Ajay Mantha (Partner), Ben Snedeker (Partner & Head of Public Equities), Diamantis Xylas, M.D. (Partner & Head of Research), Hai Yan, Ph.D. (Partner).

Is Catalio Capital Management active right now?

No recent activity since September 2026.

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