Karen Spilizewski

Karen Spilizewski

Managing Director atRiverVestCleveland, Ohio

Karen Spilizewski is a Managing Director at RiverVest Venture Partners, focusing on early-stage medical device technologies. She joined in 2008, previously worked at BioEnterprise and Avery Dennison, and holds degrees from Case Western Reserve University.

What Karen can write

Writes checks of$3M to $30M
Comes in atPre-seed, Seed, Series A, Series BCan lead the round
Ownership target7-10%At first check
Email the firm[email protected]The firm's own inbox for founders.

RiverVest writes $3M to $30M checks, larger than 93% of firms in the atlas.

Bars: how many firms report each check band. Highlighted: RiverVest.

Career

  1. Avery Dennison Corporation
  2. BioEnterprise · vice president
    until 2020
  3. RiverVest Venture Partners · Vice President
    Now
  4. RiverVest Venture Partners · Managing Director
    Now
  5. Avery Dennison Corporation
  6. RiverVest · Vice President
    Now
  7. RiverVest · Managing Director
    Now

Investments named in public bios

Flex Vascular (formerly VentureMed Group)Securus Medical GroupStandard BariatricsNeuros MedicalFlex VascularVentureMed Group

Focus

medical deviceslife sciencesearly-stagemedical device technologieslife science

Education

Case Western Reserve University, M.B.A.

Also at RiverVest

Partners like Karen

At firms with a similar stage, sector and check size.

Alert me when RiverVest is active

One email when Karen's firm raises a fund, adds a partner or shows new activity.

Founders and investors at a Mode VC gathering

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Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

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Questions

Who is Karen Spilizewski?

Karen Spilizewski is a Managing Director at RiverVest Venture Partners, focusing on early-stage medical device technologies. She joined in 2008, previously worked at BioEnterprise and Avery Dennison, and holds degrees from Case Western Reserve University.

How much does Karen Spilizewski invest?

Karen Spilizewski invests through RiverVest, which writes checks of $3M to $30M at pre-seed, seed, series a, series b.

How do I pitch Karen Spilizewski?

Email [email protected], the firm's inbox for founders, and name Karen in the subject. A warm intro from a founder RiverVest backed works better.

What did Karen Spilizewski do before RiverVest?

Avery Dennison Corporation; vice president at BioEnterprise; Avery Dennison Corporation.

Last updated 2026-10-15. Is this you? Ask for a correction.