Stephen Knight

Stephen Knight

Senior Managing Partner atF-Prime CapitalCambridge

Stephen Knight is President and Senior Managing Partner at F-Prime, where he has worked since 2003. He invests broadly across healthcare and serves on multiple boards.

What Stephen can write

Writes checks of$1M to $30M+
Comes in atPre-seed, Seed, Series A, Series BCan lead the round
Ownership target7-10%At first check
Email the firm[email protected]The firm's own inbox for founders.

F-Prime Capital writes $1M to $30M+ checks, larger than 83% of firms in the atlas.

Bars: how many firms report each check band. Highlighted: F-Prime Capital.

Career

  1. AT&T Bell Laboratories · researcher
  2. National Institutes of Health · researcher
  3. Yale University · researcher
  4. F-Prime · President & Senior Managing Partner
    Now
  5. Columbia University
  6. F-Prime Capital · President & Senior Managing Partner
    Now

Investments named in public bios

Atalanta TherapeuticsLeyden LabsParadigmQuarry TheraXaira TherapeuticsBeam TherapeuticsBlueprint MedicinesDenali TherapeuticsFoldRx PharmaceuticalsInnovent BiologicsIora HealthIronwood PharmaceuticalsNextWave PharmaceuticalsPrime MedicineQuantum Circuits, Inc.Respivert, Ltd

Focus

healthcarebiotechnologypharmaceuticalspharmaceutical

Education

Yale University School of Medicine, MDYale School of Organization and Management, MBAColumbia University, BS in biology

Also at F-Prime Capital

Partners like Stephen

At firms with a similar stage, sector and check size.

Alert me when F-Prime Capital is active

One email when Stephen's firm raises a fund, adds a partner or shows new activity.

Founders and investors at a Mode VC gathering

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Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

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Questions

Who is Stephen Knight?

Stephen Knight is President and Senior Managing Partner at F-Prime, where he has worked since 2003. He invests broadly across healthcare and serves on multiple boards.

How much does Stephen Knight invest?

Stephen Knight invests through F-Prime Capital, which writes checks of $1M to $30M+ at pre-seed, seed, series a, series b.

How do I pitch Stephen Knight?

Email [email protected], the firm's inbox for founders, and name Stephen in the subject. A warm intro from a founder F-Prime Capital backed works better.

What did Stephen Knight do before F-Prime Capital?

researcher at AT&T Bell Laboratories; researcher at National Institutes of Health; researcher at Yale University; Columbia University.

Last updated 2026-10-15. Is this you? Ask for a correction.