Pre-seed investors in Massachusetts

36 of 49 pre-seed firms that report a preference say they can lead. 3 active since September.

Can leadMostly followsNot reportedRecently active
Founder CollectiveActive Sep 29
Massachusetts
Amanda Herson, David Frankel+2 on the team
Pre-seedSeedLeadsGeneralistConfirmed by the firm
$1M to $3MCan lead
The EngineActive Sep 22
Massachusetts · Fund $398M (Fund III) (2024)
Ann DeWitt, Israel Ruiz+9 on the team
Pre-seedSeedSeries ALeadsDeep tech +4
$250K to $10MCan lead
ConvergeActive Sep 27
Massachusetts
Anshu Agarwal, Maia Heymann+3 on the team
Pre-seedSeedSeries AEnterprise software +4
Check size not reportedLead not reported
Massachusetts · Fund $37M (2022)
Giuseppe Stuto, Julian Fialkow
Pre-seedSeedLeadsGeneralistConfirmed by the firm
$500K to $1MCan lead
Massachusetts
Dwight Poler, Ryan Macpherson+1 on the team
Pre-seedSeedLeadsClimate +3
Check size not reportedCan lead
Massachusetts
Andy Feinberg, Bob Mason
Pre-seedSeedSeries ALeadsGeneralist
$250K to $500KCan lead
Massachusetts · Fund $239M
Amy Duffuor, Johanna Wolfson+5 on the team
Pre-seedSeedLeadsClimate +2
Check size not reportedCan lead
Massachusetts · Fund $350M
David Fallace, J.D. / M.B.A., Lou Tartaglia, Ph.D.+13 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +1
Check size not reportedCan lead
Massachusetts
Campbell Murray, Daniel Yadegar
Pre-seedSeedSeries ALeadsLife sciences +1
Check size not reportedCan lead
Massachusetts
Alex Benik
Pre-seedSeedLeadsDev tools and infra
$250K to $1MCan lead
Massachusetts
Stephen Knight, Amber Cai+17 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +4
$1M to $30M+Can lead
Massachusetts
Jennifer Uhrig, Shyam Kamadolli+4 on the team
Pre-seedSeedSeries ASeries BLeadsDeep tech
Check size not reportedCan lead
Massachusetts · Fund $2.6B
Paul Biondi, Doug Cole, M.D.+1 on the team
Pre-seedSeedLeadsLife sciences +2
Check size not reportedCan lead
Massachusetts · Fund $100M (2025)
Chip Hazard, Jeff Bussgang+2 on the team
Pre-seedSeedLeadsDev tools and infra +1
$100K to $3MCan lead
Massachusetts · Fund $200M+ Fund III (2025)
Kleida Martiro, Rick Grinnell+4 on the team
Pre-seedSeedLeadsDeep tech +2
Check size not reportedCan lead
Massachusetts
John Murphy, Vivjan Myrto+2 on the team
Pre-seedSeedSeries ALeadsDeep tech +4
$250K to $3MCan lead
Massachusetts · Fund $21M (2020)
Joe Gerber, Reuben Brama
Pre-seedSeedLeadsCrypto +2
$250K to $3MCan lead
Massachusetts · Fund $40 million
Alexander Lange, Jonatan Luther-Bergquist
Pre-seedSeedLeadsDefense and space +4
$500K to $1MCan lead
Massachusetts
Max Krause, Venkat Srinivasan+4 on the team
Pre-seedSeedLeadsGeneralistConfirmed by the firm
$250K to $3MCan lead
Massachusetts · Fund $250 million (2025)
Alexander Harstrick, Jonathan Bronson+3 on the team
Pre-seedSeedSeries ALeadsDeep tech +4
$1M to $10MCan lead
Massachusetts
Jean Hammond, Matthew J. Rubins+3 on the team
Pre-seedLeadsEducation and work
$100K to $3MCan lead
Massachusetts
Christoph Westphal, Rich Aldrich+4 on the team
Pre-seedSeedSeries ALeadsLife sciences
Check size not reportedCan lead
Massachusetts · Fund $100M (2023)
Adrian Mendoza, Senofer Mendoza+3 on the team
Pre-seedSeedSeries ALeadsFintech +2
$500K to $3MCan lead
Massachusetts · Fund $143.75M
Douglas Crawford, Johannes Fruehauf+10 on the team
Pre-seedSeedSeries ALeadsLife sciences
$25K to $10MCan lead
Massachusetts
Nichola Eliovits, Johnny Hatem+2 on the team
Pre-seedSeedSeries ALeadsDeep tech +2
$250K to $10MCan lead
Massachusetts
Eugene Malobrodsky, Lex Zhao+2 on the team
Pre-seedSeedLeadsDeep tech
Check size not reportedCan lead
Massachusetts · Fund $80.52 (2020)
David Martirano, Matt Hayes+3 on the team
Pre-seedSeedSeries ALeadsGeneralist
$500K to $3MCan lead
Massachusetts · Fund $118 million Fund I
Brian Halligan, Devdutt Yellurkar+3 on the team
Pre-seedSeedSeries ALeadsClimate +3
$500K to $3MCan lead
Massachusetts · Fund $260 (2022)
Anna French, Mark McDade+4 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +1
$1M to $10MCan lead
Massachusetts · Fund $10B+ (2025)
Adam Kaye, Emily Minkow+35 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +4
$3M to $30M+Can lead
Massachusetts
Jay Po, Mark Roberge+6 on the team
Pre-seedSeedSeries ALeadsGeneralistConfirmed by the firm
$100K to $10MCan lead
Massachusetts · Fund $269M (2025)
Greg Madden, Kate Bingham+19 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +1
Check size not reportedCan lead
Massachusetts
Juan Luis Leungli, Matthew Rhodes-Kropf+2 on the team
Pre-seedSeedSeries ALeadsEnterprise software +1
Check size not reportedCan lead
Massachusetts
Ariel Winton-Jones
Pre-seedSeedLeadsEnterprise software
Check size not reportedCan lead
Massachusetts
Calvin Chin, Habib Haddad+1 on the team
Pre-seedSeedSeries ALeadsDeep tech
$25K to $10MCan lead
Massachusetts
Brian Devaney, Chris Gardner+2 on the team
Pre-seedSeedLeadsGeneralistConfirmed by the firm
$500K to $3MCan lead
Massachusetts · Fund US$262.5M
Ben Nye, Anton Simunovic
Pre-seedSeedLeadsDev tools and infra
Check size not reportedCan lead
Massachusetts
Fady Saad, Mark Martin
Pre-seedSeedSeries ADeep tech +7
Check size not reportedLead not reported
Massachusetts
Hiromichi Kimura, Tomohiro Anzai+1 on the team
Pre-seedSeedSeries ALife sciences +1
Check size not reportedLead not reported
Massachusetts
Andrew Spellman, Janki Gandhi+3 on the team
Pre-seedSeedSeries ASeries BGeneralist
Check size not reportedLead not reported

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Questions

How many pre-seed investors in massachusetts are there?

Mode VC tracks 58 firms on this list as of 2026-10-15. 3 have been active since September 2026.

What check size do pre-seed investors in massachusetts write?

The most reported band is $1M to $3M, reported by 22 firms on this list.

Which pre-seed investors in massachusetts lead rounds?

36 of 49 firms that report a preference say they can lead. Turn on "Leads rounds" to see only them.