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Seed life sciences investors in Massachusetts

17 of 22 seed life sciences firms that report a preference say they can lead. 2 active since September.

Can leadMostly followsNot reportedRecently active

The EngineActive Sep 22

Massachusetts · Fund $398M (Fund III) (2024)

Ann DeWitt, Israel Ruiz+9 on the team

Pre-seedSeedSeries ALeadsDeep tech +4

$250K to $10MCan lead

Safar PartnersActive Oct 13

Massachusetts · Fund More than $1 billion AUM

Arunas Chesonis, Nader Motamedy+6 on the team

SeedSeries ASeries BLeadsClimate +2

Check size not reportedCan lead

Massachusetts · Fund $450M Fund XIV (2026)

Bruce Booth, David Grayzel+10 on the team

SeedSeries ALeadsLife sciences

Check size not reportedCan lead

Broadview Ventures

Massachusetts

Daniel Gottlieb, Thomas Needham+5 on the team

SeedSeries ALeadsLife sciences +1

Check size not reportedCan lead

Massachusetts · Fund $350M

David Fallace, J.D. / M.B.A., Lou Tartaglia, Ph.D.+13 on the team

Pre-seedSeedSeries ASeries BLeadsLife sciences +1

Check size not reportedCan lead

Double Point Ventures

Massachusetts

Campbell Murray, Daniel Yadegar

Pre-seedSeedSeries ALeadsLife sciences +1

Check size not reportedCan lead

F-Prime Capital

Massachusetts

Stephen Knight, Amber Cai+17 on the team

Pre-seedSeedSeries ASeries BLeadsLife sciences +4

$1M to $30M+Can lead

Flagship Pioneering

Massachusetts · Fund $2.6B

Paul Biondi, Doug Cole, M.D.+1 on the team

Pre-seedSeedLeadsLife sciences +2

Check size not reportedCan lead

Massachusetts · Fund $250 million (2025)

Alexander Harstrick, Jonathan Bronson+3 on the team

Pre-seedSeedSeries ALeadsDeep tech +4

$1M to $10MCan lead

Massachusetts

Christoph Westphal, Rich Aldrich+4 on the team

Pre-seedSeedSeries ALeadsLife sciences

Check size not reportedCan lead

Mission BioCapital

Massachusetts · Fund $143.75M

Douglas Crawford, Johannes Fruehauf+10 on the team

Pre-seedSeedSeries ALeadsLife sciences

$25K to $10MCan lead

Massachusetts · Fund $470.0M Fund VIII

Francesco Draetta, Bernard Davitian+9 on the team

SeedSeries ASeries BLeadsLife sciences

$10M to $30M+Can lead

Qiming Venture Partners USA

Massachusetts · Fund $260 (2022)

Anna French, Mark McDade+4 on the team

Pre-seedSeedSeries ASeries BLeadsLife sciences +1

$1M to $10MCan lead

RA Capital Management

Massachusetts · Fund $10B+ (2025)

Adam Kaye, Emily Minkow+35 on the team

Pre-seedSeedSeries ASeries BLeadsLife sciences +4

$3M to $30M+Can lead

Remiges Ventures

Massachusetts · Fund US$100M

Taro Inaba, Kazuhiko Nonomura+4 on the team

SeedLeadsLife sciences

Check size not reportedCan lead

Massachusetts

Erica Murdock, Jason Robart+6 on the team

SeedSeries ALeadsHealthtech +1Confirmed by the firm

$1M to $3MCan lead

SV Health Investors

Massachusetts · Fund $269M (2025)

Greg Madden, Kate Bingham+19 on the team

Pre-seedSeedSeries ASeries BLeadsLife sciences +1

Check size not reportedCan lead

Blindspot Ventures

Massachusetts

Ahmed Hentati, Hassan Dayekh+1 on the team

SeedDev tools and infra +4

Check size not reportedLead not reported

Fast Track Initiative, Inc.

Massachusetts

Hiromichi Kimura, Tomohiro Anzai+1 on the team

Pre-seedSeedSeries ALife sciences +1

Check size not reportedLead not reported

Four Cities Capital

Massachusetts

Ben Hutchinson, George Davies+1 on the team

Pre-seedSeedDev tools and infra +5

Check size not reportedMostly follows

Massachusetts · Fund $250 million+ AUM (2016)

Lucio Iannone, Ph.D., Sylvia Tobé, Ph.D.+5 on the team

SeedSeries ASeries BLife sciences +1

Check size not reportedMostly follows

LiquidMetal Ventures

Massachusetts · Fund $10 million (2022)

Ji Zhao, Qiong Ye+2 on the team

Pre-seedSeedSeries ALife sciences +2

Check size not reportedLead not reported

Massachusetts

Myron Kassaraba, Priya Yadav+2 on the team

Pre-seedSeedDeep tech +2

Check size not reportedLead not reported

Massachusetts · Fund $50M commitment

Christopher D. Hillyer, Meg Wood+2 on the team

SeedSeries ASeries BLife sciences

Check size not reportedLead not reported

Polaris Partners

Massachusetts

Alexandra Cantley, Amy Schulman+7 on the team

SeedSeries AHealthtech +1

$500K to $10MMostly follows

Massachusetts

Fred Callori, Gianna Hoffman-Luca+4 on the team

SeedLife sciences

Check size not reportedMostly follows

Massachusetts

Daguang Wang

SeedSeries ASeries BLife sciences

Check size not reportedMostly follows

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Related lists

Seed life sciences investors186 Seed investors in Massachusetts95 Seed life sciences investors in California71 Seed life sciences investors in New York26 Seed healthtech investors in Massachusetts25 Series A life sciences investors in Massachusetts22 Seed climate investors in Massachusetts19 Seed deep tech investors in Massachusetts19 Pre-seed life sciences investors in Massachusetts16 Seed industrial investors in Massachusetts14 Seed enterprise software investors in Massachusetts12 Seed dev tools and infra investors in Massachusetts12

Questions

How many seed life sciences investors in massachusetts are there?

Mode VC tracks 27 firms on this list as of 2026-10-15. 2 have been active since September 2026.

What check size do seed life sciences investors in massachusetts write?

The most reported band is $1M to $3M, reported by 7 firms on this list.

Which seed life sciences investors in massachusetts lead rounds?

17 of 22 firms that report a preference say they can lead. Turn on "Leads rounds" to see only them.