Series A life sciences investors

105 of 129 series a life sciences firms that report a preference say they can lead. 9 active since September.

Can leadMostly followsNot reportedRecently active
DCVCActive Oct 8
California · Fund Billions of dollars AUM
Ali Tamaseb, James Hardiman+15 on the team
SeedSeries ALeadsDeep tech +4
$10M to $30M+Can lead
The EngineActive Sep 22
Massachusetts · Fund $398M (Fund III) (2024)
Ann DeWitt, Israel Ruiz+9 on the team
Pre-seedSeedSeries ALeadsDeep tech +4
$250K to $10MCan lead
Illinois · Fund $3B+ Fund XIII (2024)
Paul Berns, Keith Crandell+12 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +1
$25K to $30M+Can lead
Foothill VenturesActive Sep 23
California
Jinlin Wang, Max Von Poelnitz+6 on the team
SeedSeries ALeadsEnterprise software +3
Check size not reportedCan lead
Hitachi VenturesActive Oct 15
California · Fund USD400M HV Fund IV
Pete Bastien, Stefan Gabriel+19 on the team
SeedSeries ASeries BLeadsIndustrial +3
$1M to $30MCan lead
Narya CapitalActive Sep 29
Ohio · Fund $93M (2020)
Colin Greenspon, Falon Donohue
SeedSeries ALeadsDefense and space +5
$3M to $10MCan lead
Safar PartnersActive Oct 13
Massachusetts · Fund More than $1 billion AUM
Arunas Chesonis, Nader Motamedy+6 on the team
SeedSeries ASeries BLeadsClimate +2
Check size not reportedCan lead
The Longevity FundActive Sep 24
California
Alex Colville, Satvik Dasariraju
Pre-seedSeedSeries ALeadsLife sciences
$500K to $10MCan lead
CompoundActive Sep 27
New York
David Hirsch, Michael Dempsey+2 on the team
SeedSeries ADeep tech +4
Check size not reportedLead not reported
Location not listed · Fund $450M
Andy J. Schwab, John D. Diekman, PhD+14 on the team
SeedSeries ALeadsLife sciences +2
Check size not reportedCan lead
New York
Anders Hove, Isaac Manke+2 on the team
SeedSeries ASeries BLeadsLife sciences +1Confirmed by the firm
$100K to $10MCan lead
California · Fund $100M+
Manuel Gonzalez, Michael Dean+8 on the team
SeedSeries ALeadsFood and ag +2
$25K to $10MCan lead
California
Joel S. Marcus, Blake L. Stevens+2 on the team
SeedSeries ASeries BLeadsLife sciences +2
Check size not reportedCan lead
California
Bob More, Dan Janney+1 on the team
SeedSeries ASeries BLeadsLife sciences +1
$1M to $30MCan lead
Washington · Fund $60M (Fund IV) (2020)
Dave Maki, Kristen Wong
SeedSeries ASeries BLeadsLife sciences
$500K to $3MCan lead
California · Fund $400M (2025)
Lenny Pruss, Mike Dauber+8 on the team
Pre-seedSeedSeries ALeadsDev tools and infra +2
$500K to $10MCan lead
Quebec · Fund C$263M Fund II (2024)
Dion Madsen, Jean-Francois Pariseau+7 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +1
Check size not reportedCan lead
California · Fund $200 million (2025)
Ken Horne, Ari Nowacek+9 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences
Check size not reportedCan lead
District of Columbia
David Michael, David Seldin+9 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +3
Check size not reportedCan lead
New York · Fund $2.9B committed capital
Seth L. Harrison, Anna Batarina+1 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences
$10M to $30M+Can lead
Michigan · Fund $268M Fund VI (2023)
Dan Kidle, Jan Garfinkle+6 on the team
Series ASeries BLeadsHealthtech +1
Check size not reportedCan lead
Massachusetts · Fund $450M Fund XIV (2026)
Bruce Booth, David Grayzel+10 on the team
SeedSeries ALeadsLife sciences
Check size not reportedCan lead
California · Fund $60M Fund I
Christopher Male, Lauren Ingram+3 on the team
SeedSeries ASeries BLeadsHealthtech +1
Check size not reportedCan lead
California
Drew Lanza, Ted Hou+1 on the team
SeedSeries ALeadsLife sciences +2
Check size not reportedCan lead
Washington
Rob Carlson
SeedSeries ASeries BLeadsLife sciences
$100K to $10MCan lead
Florida · Fund $50M (2026)
Jamie Rutledge, Chris Cesareo+1 on the team
Pre-seedSeedSeries ALeadsDeep tech +6
$250K to $3MCan lead
California · Fund $500M+ AUM
Murray Rode, Rafi Syed+4 on the team
SeedSeries ALeadsDeep tech +5
Check size not reportedCan lead
California · Fund $114M Fund III (2026)
Julia Moore, Lindy Fishburne+2 on the team
Pre-seedSeedSeries ALeadsLife sciences +2
$500K to $10MCan lead
Massachusetts
Daniel Gottlieb, Thomas Needham+5 on the team
SeedSeries ALeadsLife sciences +1
Check size not reportedCan lead
California
Karan Wadhera, Yoni Meyer+1 on the team
Pre-seedSeedSeries ASeries BLeadsConsumer +3
Check size not reportedCan lead
New York · Fund $2B AUM
George C. Petrocheilos, R. Jacob Vogelstein, Ph.D.+18 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +1
Check size not reportedCan lead
New Jersey
Aryeh Ganz, Jinny Choi+2 on the team
Pre-seedSeedSeries ASeries BLeadsHealthtech +3
$250K to $10MCan lead
Massachusetts · Fund $350M
David Fallace, J.D. / M.B.A., Lou Tartaglia, Ph.D.+13 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +1
Check size not reportedCan lead
New York
Nan Li, Zavain Dar+3 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciencesConfirmed by the firm
$3M to $30MCan lead
Massachusetts
Campbell Murray, Daniel Yadegar
Pre-seedSeedSeries ALeadsLife sciences +1
Check size not reportedCan lead
New York
John H. Friedman, Kresimir Letinic+1 on the team
Series ASeries BLeadsHealthtech +1
$1M to $10MCan lead
Connecticut
Chris McLeod, Rob Bettigole+1 on the team
Pre-seedSeedSeries ALeadsLife sciences +3
$500K to $1MCan lead
Massachusetts
Stephen Knight, Amber Cai+17 on the team
Pre-seedSeedSeries ASeries BLeadsLife sciences +4
$1M to $30M+Can lead
California · Fund $900M (2025)
Aydin Senkut, James Detweiler+7 on the team
Pre-seedSeedSeries ALeadsCybersecurity +4
$1M to $30M+Can lead
California · Fund $900M
Hyung Chun, MD, Shannon Bergstedt+11 on the team
Pre-seedSeedSeries ASeries BLeadsHealthtech +2
Check size not reportedCan lead

Get series a life sciences investors every Monday

Only the firms on this list that show new activity. Unsubscribe in one click.

Founders and investors at a Mode VC gathering

Send Mode VC your deck

Raising a pre-seed or seed round? We write $1M to $5M first checks and help founders with distribution. A partner reads every deck.

Send your deck

Related lists

Questions

How many series a life sciences investors are there?

Mode VC tracks 167 firms on this list as of 2026-10-15. 9 have been active since September 2026.

What check size do series a life sciences investors write?

The most reported band is $3M to $10M, reported by 49 firms on this list.

Which series a life sciences investors lead rounds?

105 of 129 firms that report a preference say they can lead. Turn on "Leads rounds" to see only them.